Recombination Frequency Formula:
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Recombination frequency (RF) is a measure of genetic linkage and is used to create genetic maps. It represents the percentage of recombinant offspring among the total offspring in a genetic cross.
The calculator uses the recombination frequency formula:
Where:
Explanation: The formula calculates the percentage of offspring that show recombination between two genetic loci.
Details: Recombination frequency is crucial for genetic mapping, determining the relative positions of genes on chromosomes, and understanding genetic linkage.
Tips: Enter the number of recombinant offspring and the total number of offspring. Both values must be valid (recombinants ≥ 0, total offspring > 0, and recombinants ≤ total offspring).
Q1: What is a recombinant offspring?
A: Recombinant offspring are those that show a combination of traits different from either parent due to crossing over during meiosis.
Q2: What is the range of recombination frequency values?
A: RF values range from 0% (completely linked genes) to 50% (unlinked genes that assort independently).
Q3: How is recombination frequency related to genetic distance?
A: One percent recombination frequency equals one map unit (centimorgan) on a genetic map.
Q4: Can recombination frequency exceed 50%?
A: No, recombination frequency cannot exceed 50% for autosomal genes as this represents independent assortment.
Q5: What factors can affect recombination frequency?
A: Factors include distance between genes, chromosomal location, sex, age, and environmental conditions.