1. What is Protein To Creatinine Ratio?

The Protein To Creatinine Ratio (PCR) is a diagnostic test that measures the amount of protein in urine relative to the amount of creatinine. It's used to screen for and monitor kidney disease, particularly proteinuria.

2. How Does the Calculator Work?

The calculator uses the PCR formula:

Where:

• Protein Concentration — Measured in mg/dL
• Creatinine Concentration — Measured in mg/dL

Explanation: The ratio normalizes protein excretion to creatinine excretion, providing a more accurate assessment than random urine protein measurements alone.

3. Importance of PCR Calculation

Details: PCR is crucial for detecting and monitoring proteinuria, which is a key indicator of kidney damage. It helps in diagnosing various kidney disorders and monitoring response to treatment.

4. Using the Calculator

Tips: Enter both protein and creatinine concentrations in mg/dL. Both values must be valid (greater than 0). The result is typically expressed in mg/g creatinine.

5. Frequently Asked Questions (FAQ)

Q1: What is a normal PCR value?
A: Normal PCR is typically less than 150 mg/g. Values between 150-500 mg/g indicate microalbuminuria, and values above 500 mg/g indicate overt proteinuria.

Q2: Why use PCR instead of 24-hour urine collection?
A: PCR provides a reliable estimate of protein excretion without the inconvenience and potential errors of 24-hour urine collection.

Q3: When should PCR be measured?
A: PCR is typically measured in random urine samples, preferably first morning void, to avoid diurnal variations.

Q4: Are there limitations to PCR testing?
A: PCR may be less accurate in individuals with very high or very low muscle mass, as creatinine excretion correlates with muscle mass.

Q5: How often should PCR be monitored?
A: Frequency depends on the underlying condition. Patients with diabetes or kidney disease may need regular monitoring every 3-6 months.