1. What is Protein Creatinine Ratio?

The Protein Creatinine Ratio (PCR) is a simple test used to estimate the amount of protein excreted in urine. It's calculated by dividing the urine protein concentration by the urine creatinine concentration, providing a more accurate assessment than a random urine protein test alone.

2. How Does the Calculator Work?

The calculator uses the PCR formula:

Where:

• Protein — Urine protein concentration (mg/dL)
• Creatinine — Urine creatinine concentration (mg/dL)

Explanation: This ratio corrects for variations in urine concentration, providing a more reliable measure of protein excretion than protein measurement alone.

3. Importance of PCR Calculation

Details: PCR is used to screen for, detect, and monitor kidney disease. It helps identify proteinuria, which is a key marker of kidney damage and a risk factor for progression of kidney disease.

4. Using the Calculator

Tips: Enter both protein and creatinine values in mg/dL. Both values must be greater than zero. The result is expressed in mg/g creatinine.

5. Frequently Asked Questions (FAQ)

Q1: What is a normal PCR value?
A: Normal PCR is typically less than 150 mg/g. Values between 150-500 mg/g indicate microalbuminuria, while values above 500 mg/g indicate overt proteinuria.

Q2: Why use PCR instead of 24-hour urine collection?
A: PCR provides a reliable estimate of protein excretion without the inconvenience and potential errors of 24-hour urine collection.

Q3: When should PCR be measured?
A: First morning urine sample is preferred as it provides the most concentrated specimen and minimizes orthostatic proteinuria.

Q4: Are there limitations to PCR?
A: PCR may be less accurate in people with very high or very low muscle mass, as creatinine excretion correlates with muscle mass.

Q5: How often should PCR be monitored?
A: Frequency depends on the underlying condition. People with diabetes or kidney disease may need annual screening, while those with established proteinuria may need more frequent monitoring.